
AestheFill is an advanced collagen stimulator formulated from Poly-D, L-Lactic Acid (PDLLA), a biocompatible and biodegradable synthetic polymer with a concentration of 200 mg that stimulates the body's natural collagen production over time. AestheFill is a type of collagen stimulator used in aesthetic medicine for facial rejuvenation. It is designed to improve skin texture, increase volume, and reduce the appearance of wrinkles and fine lines. The PDLLA microspheres in AestheFill® are designed with a porous external surface and a sponge-like internal structure. This three-dimensional design allows fibroblasts to promote collagen fiber formation around, between and within the microspheres.

Injectable collagen biostimulator
200mg
12 - 16 months
2 - 3 sessions, every 4 - 6 weeks
PDLLA (Poly-D,L-Lactic Acid)
REGEN Biotech, Inc.

The PDLLA microspheres in AestheFill are designed with a porous external surface and a sponge-like internal structure. This three-dimensional design allows fibroblasts to promote collagen fiber formation around, between and within the microspheres. This microsphere design helps support the products' aesthetic profile: natural-looking support, progressive renewal and controlled distribution when prepared and administered.
Immediate natural-looking improvement with progressive collagen stimulation and results lasting 12 months or longer that result in natural and smooth skin texture and restored elasticity.
Fast preparation and ready for immediate use, with procedures taking approximately 15–30 minutes (less than 30 minutes of reconstitution time).
Biodegradable PDLLA with over 12 years of clinical use and a low reported rate of treatment-related adverse effects with less Nodule formation and less risk of migration.
Customizable treatment options for skin quality, facial rejuvenation and body contouring, patented porous microspheres provide spaces for collagen formation.
No post-treatment message required.
AestheFill® cases illustrate progressive, natural-looking change over time. Outcomes include improved facial contours, softening of lines and folds, improvement in depressed acne scars and sustained correction at long-term follow-up. Individual results vary according to anatomy, tissue condition, technique and treatment plan.

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